World Youth Skills Day 2022 takes place amid concerted efforts towards socio-economic recovery from the COVID-19 pandemic that are interconnected with challenges such as climate change, conflict, persisting poverty, rising inequality, rapid technological change, demographic transition and others. In 2014, the United Nations General Assembly declared 15 July as World Youth Skills Day, to celebrate the strategic importance of equipping young people with skills for employment, decent work and entrepreneurship. Since then, World Youth Skills Day has provided a unique opportunity for dialogue between young people, technical and vocational education and training (TVET) institutions, firms, employers’ and workers’ organizations, policy-makers and development partners. Due to a number of issues, young women and girls, young people with disabilities, young people from lower-income families, rural areas, indigenous peoples, and minority groups, as well as those who experience the effects of violent conflict and political instability, continue to be excluded. Additionally, the crisis has hastened a number of shifts that the workplace was already undergoing, which raises questions about the knowledge and abilities that will be in demand once the pandemic is contained. The United Nations and its agencies, such as UNESCO-UNEVOC, are well placed to help address these challenges by reducing access barriers to the world of work, ensuring that skills gained are recognized and certified, and offering skills development opportunities for out-of-school youth and those not in employment, education or training (NEET). During this Decade of Action for the 2030 Agenda, the full engagement of young people in global processes is vital to generate positive change and innovation. By assisting youth and adults in developing the skills necessary for employment, respectable work, and entrepreneurship, promoting equitable, inclusive, and sustainable economic growth, and assisting in the transition to green economies and environmental sustainability, TVET is expected to address the multiple demands of an economic, social, and environmental nature.