Due to the rising COVID-19 cases of the Omicron sub-variant, Prime Minister Shahbaz Sharif has ordered the immediate restoration of the National Command and Operation Centre (NCOC) that was disbanded in March after the country had seen an improvement in the virus situation. On March 31, Pakistan announced the closure of the NCOC, the body which was set up in March 2020 in the wake of the COVID-19 pandemic to collect, analyses and process information, transferring all its functions, roles and responsibilities to the National Institute of Health (NIH). Two days ago, Pakistan had detected its first case of the Omicron sub-variant, as the public got back to routine life after Eid-ul-Fitr celebrations without COVID-19 restrictions for the first time in two years. This Omicron subtype is highly infectious, more so than its predecessor. As per some reports, it is about 30% more transmissible than the prior Omicron iterations. The sub-lineage, BA.2.12.1, is already accounting for a growing share of coronavirus infections in the United States. As per the US Centers for Disease Control and Prevention, BA.2.12.1 was found in 36% of the samples sequenced in the last week of April, up from 0.2% in late February. While it is known to spread faster, it is still unclear if this variant is more or less deadly than the original Omicron or Delta. This Omicron sub-variant of the coronavirus was first identified six months back. While in the United States it was detected in April in New York. Doctors are still studying the variant to determine its exact symptoms, but some cases of the sub-variant suggest that it also has flu-like symptoms, similar to the Omicron variant. Therefore, those infected could experience sneezing, coughing, sore throat, fatigue and dizziness. The pandemic has not ended yet but undergoing a new phase, therefore, the precautions and preventive measures are necessary to avoid from the catastrophes of the virus.